Flexeril, Amrix cyclobenzaprine dosing, indications, interactions, adverse effects, and more
Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. The kidneys of older adults may not work as well as they used to. As a result, more of a drug stays in your body for longer. Your doctor may start you on a lowered dose or a different dosing schedule.
- You should not need a new prescription for this medication to be refilled.
- Monitoring of plasma drug levels should not guide management of the patient.
- All generic medications sold through Blink Health are FDA-approved.
- Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs.
- A post-marketing surveillance program was carried out in 7607 patients with acute musculoskeletal disorders, and included 297 patients treated with FLEXERIL 10 mg for 30 days or longer.
- If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug.
It works by blocking signals between motor nerves to relax muscle tone. It is usually taken as a 2 mg or 4 mg tablet every six to eight hours. Flexeril is known to cause serotonin syndrome, especially when taken with certain antidepressants, MAO inhibitors, and opioids. Signs and symptoms of serotonin syndrome should be monitored when starting treatment with Flexeril. Dosage may be increased every 1 to 4 days by 2 mg to 4 mg. However, the half-life of immediate-release cyclobenzaprine is 18 hours on average, with a range of 8-37 hours.
Take this medication by mouth with or without food as directed by your doctor, usually once daily. Doing so can release all of the drugs at once, increasing the risk of side effects. The most common side effects of Flexeril include drowsiness, dry mouth, headache, fatigue, and dizziness. Flexeril is also known to cause other side effects such as constipation and nausea. Flexeril (What is Flexeril?) is a brand-name drug originally FDA-approved in 1977. The generic version of Flexeril, cyclobenzaprine, is widely available.
FDA Drug Information
The dosage is based on your medical condition and response to treatment. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses. Drowsiness is the most commonly reported side effect in studies, occurring in up to 38% (38 out of 100) of people.
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Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. Methocarbamol can be used for long or short-term treatment as advised by a doctor. On the other hand, cyclobenzaprine is generally flexeril starting dose not prescribed for longer than two or three weeks. For more information on adverse effects you may experience while taking Cyclobenzaprine, please visit the National Institutes of Health’s DailyMed webpage for valsartan & cyclobenzaprine.
How to take Cyclobenzaprine (Flexeril)?
Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first. The combination of Flexeril and alcohol can cause serious problems in the central nervous system, the consequences of which may end up being fatal. The problem with combining Flexeril and alcohol comes from the fact that both of these drugs are actually central nervous system (CNS) depressants.
A Flexeril overdose can cause severe health problems such as cardiac arrest, dangerously low blood pressure, and seizures. Central nervous system depression, seizures, heart attack, and even death can occur. Robaxin is the brand name of the generic medication called methocarbamol. It was developed in the 1960s to treat pain and provide relief from muscle spasms. It is also believed that Robaxin relaxes the muscle by having depressive effects on the central nervous system. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products.
Other Side Effects
Both medications can cause adverse effects such as dizziness, drowsiness, headache, nausea, and fatigue. Cyclobenzaprine tends to cause more drowsiness than methocarbamol. Also, cyclobenzaprine can cause dry mouth because it has anticholinergic effects.
Observation with cardiac monitoring and observation for signs of CNS or respiratory depression, hypotension, cardiac dysrhythmias and/or conduction blocks, and seizures is necessary. If signs of toxicity occur at any time during this period, extended monitoring is required. Monitoring of plasma drug levels should not guide management of the patient. Dialysis is probably of no value because of low plasma concentrations of the drug. It is not known whether this drug is excreted in human milk. Your dose will depend on the severity of your pain and the formulation of cyclobenzaprine you’re using.
This is more likely to happen in the few hours after you take it. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine.
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